Using skin as a model system, mouse genetics, and human samples, our research aims to understand how the interactions between epithelial progenitor cells, and also with their surrounding microenvironment, sustain skin homeostasis, regeneration, and when perturbed lead to cancer. This information may provide insights into the future development of regenerative and anti-cancer therapies.
Our research interests fall into three categories:
Cell adhesion, cell polarity and cytoskeleton proteins in the regulation of skin stem cell’s self-renewal and differentiation.
Contributions of stromal cells, in particular immune and endothelial cells, to the skin stem cell niche during skin homeostasis.
Contributions of stromal cells, in particular immune and endothelial cells, to cancer stem cell maintenance and tumor progression.
Opportunities are potentially available for talented graduate students, postdocs and undergraduates. For inquiries, please contact Associate Professor Mirna Perez-Moreno providing the following:
- Updated CV (including academic records and names of at least 2 references).
- Motivation Letter, stating research interests and goals, educational & research background.